CHANLAB
Lectures
Jan 17 - Chapter 17.1, 17.2 (Qs: 17.20, 17.21, 17.22, 17.23)
YT Video (Stability of carbocations, radicals, and carboanions)
Jan 19 - Chapter 17.3, 17.4, 17.5 (Qs: 17.24 (1-6), 17.26 (b, c, e, f, g))
Jan 22 - Chapter 17.6, 17.7, 17.8, 17.9 (Qs: 17.26.7, 17.25c, 17.26b-e and i)
Jan 24 - Chapter 17.10, 18.1, 18.2 (Qs: 17.36, 17.37, 17.57, 18.46, 18.47)
Jan 26 - Chapter 18.3, 18.4 (Qs: 18.3, 18.4, 18.5, 18.48)
Publication from Dr. Chan's lab that uses SNAr chemistry for cancer diagnostics and drug delivery
Jan 29 - Chapter 18.4 cont., 18.5 (Qs: Be familiar with the elementary steps covered in lecture)
Jan 31 - Chapter 18.5 cont., 18.6, 18.7, 18.9 (Qs: 18:50, 18.51, 18.53a-d, g, k, l, 18.61, 18.62d, 18.30, 18.31, 18.32, 18.40a)
Look up the following TM-catalyzed reactions - Heck Reaction, Suzuki, Buchwald–Hartwig, Stille
Feb 2 - Chapter 19.1, 19.3, 19.4 19.5 (Qs: 19.3, 19.42, 19.44b)
Feb 5 - Chapter 19.5 cont., 19.6, 19.7 (Qs: read ahead 19.8 and 19.9 and try all 'Focused Problems')
Feb 7 - Chapter 19.7, 19.8, 19.9, 19.10 (Qs: 19.10, 19.11, 19.13, 19.15, 19.16, 1917, 19.18, 19.21, 19.22)
Feb 9 - Chapter 19.11 (Qs: 19.23, 19.24, 19.25)
Recorded Zoom Lecture
Feb 12 - Chapter 19.11 cont. (Qs: be familar with mechanism of ketal/acetal formation and removal)
Feb 14 - Midterm #1 Key
Feb 16 - Chapter 19.12, 19.13, 19.14, 19.15, 19.16 (Qs: TBD, read 19.15 and 19.16)
Feb 19 - Chapter 20 introduction
Feb 21 - Chapter 20.2, 20.3, 20.4, 20.5 (Qs: 20.7, 20.8, 20.31, 20.36, 20.37, 20.38, 20.39, 20.41 and read Chapter 20.3)
Feb 23 - Chapter 20.6, 20.7, 20.8, 20.9 (Qs: 20.9, 20.10, 20.11b, 20.12b, 20.13, 20.14)
Feb 26 - Chapter 20.9 cont., 20.10, 20.11 (Qs: 20.15, 20.16, 20.20)
Feb 28 - Chapter 20.11 cont., 21.1, 21.2, 21.3, 21.4 (Qs: N/A)
Mar 1 - Chapter 21.6, 21.7, 21.8 (Qs: 21.5, 21.6a, 21.9a-c, 21.10, 21.11, 21.12, 21.14)
Mar 4 - Chapter 21.8 cont. 21.9 (Qs: 21.15, 21.16a,c,d, 21.17a, 21.18, 21.19b,c, 21.20)
* will also need to know Weinreb Amide chemistry, please see and refer to the following links:
Link 1 / Link 2
Mar 18 - Chapter 22.1, 22.2, 22.3, 22.4 (Qs: 22.12, 22.13, 22.14, Study Problem 22.1)
Link to Recorded Lecture #2 (available online for 30 days only)
Link to Recorded Lecture #2 (available online for 30 days only)
Mar 20 - Chapter 22.4 cont., 22.5, 22.6, 22.9 (Qs: 22.20, 22.21, 22.26, 22.27, 22.28, 22.29, 22.30c-d, 22.31)
Link to Recorded Lecture #3 (available online for 30 days only)
Mar 22 - Lecture Notes
Mar 23 - Review Session #1 Recording (available online for 30 days only)
Mar 24 - Review Session #2 Recording (available online for 30 days only)
Mar 27 - Chapter 22.9 cont., 22.10, 22.11 (Qs: 22.43a-b, 22.44a-b, 22.45b, 22.46, 22.48, 22.50)
Mar 29 - Chapter 22.12, 23.1, 23.2, 23.3 (Qs: 22.51a,c, 22.67a-j)
Apr 1 - Chapter 23.3 cont., 23.4 (Qs: 23.13, 23.14, Study Problem 23.1)
Apr 3 - Chapter 23.4, 23.5, 23.6, 23.7 (Qs: 23.7, 23.8, 23.12)
Apr 8 - 23.7, 23.8 (Qs: 23.11, 23.12, 23.15, 23.16, 23.23)
Apr 10 - Chapter 23.9, 23.10 (Qs: 23.26, 23.29a-b, study problem 23.5, 23.37)
Apr 12 - Lecture Notes
Link to Recorded Lecture (available online for 30 days only)
Apr 15 - Chapter 27 (Qs: 23.40, 23.41, 27.1b, 27.2, 27.3)
Apr 17 - Chapter 27 cont.
Apr 19 - Chapter 27 cont. (Midterm #3 cut-off)
Apr 22 - Chemistry of Sulfur
Homework Assignments
Assignment #1 (Due Friday Feb 2, 2024) - Answer Key
Assignment #2 (Due Wednesday Feb 14, 2024 before Midnight) - Answer Key
Assignment #3 (Due Wednesday Feb 28, 2024) - Answer Key
Assignment #4 - See Review Session Recording for More Details
Assignment #5 - Answer Key
Assignment #6 (Due Monday Apr 8, 2024)
Assignment #7 (Due Wednesday Apr 24, 2024)
Assignment #8 (Due Wednesday Apr 24, 2024)
Midterm Exams
Midterm #1 (Will cover lecture material from Chapter 17, 18, and up to 19.11 (Chapter 19.12-19.5 will be MT2 material)
Midterm #1 (2022) / Answer Key
Practice Midterm #1 (2023) / Answer Key
Midterm #2 (Will cover lecture material from Chapter 19.12 to 22.8)
Midterm #2 (2023) / Answer Key
Midterm #3 (Will cover lecture material from rest of Chapter 22, 23, 27)
Midterm #3 (2023) / Answer Key
Review Session #1 via Zoom (Saturday April 20, 2024 11 am to 12 pm)
Review Session #2 via Zoom (Monday April 22, 2024 11 am to 12 pm)
Extra Office Hours (Tuesday April 23, 2024 11:30 to 12:15 pm)
Extra Office Hours via Zoom (Tuesday April 23, 2024 8:00 to 8:30 pm)
https://illinois.zoom.us/j/7272620682?pwd=MW9kcHZ0STYwL1hXa2JRWExVUGxxUT09
Meeting ID: 727 262 0682
Password: probes
Final Exam
Extra Office Hours
May 5 via Zoom 8-9 pm
May 6 via Zoom 8-8:45 pm
May 8 in-person regular time
May 9 via Zoom 8-9 pm
© CHANLAB 2024