CHANLAB

Dr. Keith Coffman

BS Chemistry, University of California Davis

PhD Chemistry, University of California Davis

 

Postdoctoral Research Associate

 

Publications

5. Coffman KC, Doung V, Palazzo TP, Fettinger JC, Haddadin MJ, Kurth MJ. Heterocycle-to-heterocycle route to quinoline-4-amines: Reductive heterocyclization of 3-(2-nitrophenyl)isoxazoles. Eur. J. Org. Chem. 2014, 34, 7651-7657.

 

4. Coffman KC, Nguyen HH, Phuan P.-W, Hudson BM, Yu GJ, Bagdasarian AL, Montgomery D, Lodewyk MW, Yang B, Yoo CL, Verkman AS, Tantillo DJ, Kurth MJ. Constrained bithiazoles: Small molecule correctors of defective ∆F508-CFTR protein trafficking. J. Med. Chem, 2014, 57, 6729–6738.

 

3. Coffman KC, Palazzo TA, Hartley TH, Fettinger JC, Tantillo DJ, Kurth MJ. Heterocycle-Heterocycle strategies: (2-nitrophenyl)isoxazoles to 4-aminoquinolines, 1H-indoles, and quinolin-4(1H)-ones. Org. Lett. 2013, 15, 2062-2065.

 

2. Coffman KC, Hartley TP, Dallas JL, Kurth MJ. Isoxazolodihydropyridinones: 1,3-Dipolar cycloaddition of nitrile oxides onto 2,4-dioxopiperidines. ACS Comb. Sci. 2012, 14, 280-284.

 

1. Butler JD, Coffman KC, Kurth MJ. Orthogonally protected thiazole and isoxazole diamino acids: An efficient synthetic route. Chem. Eur. J. 2010, 16, 9002-9005.

 

Select Awards

1. Tara K. Telford Graduate Student Award (2013)