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Dr. Anuj Yadav
PhD in Chemistry, NCL India
Postdoc, SFU
Publications
14. Zhao Z, Yadav AK, Weng Y, Chan J. Development of nitroreductase-activatable fluoroquinolone prodrugs exhibiting attenuated magnesium ion binding. Helv. Chim. Acta. 2023, Submitted.
13. Yadav AK, Chan J. Activity-based bioluminescence probes for in vivo sensing applications. Curr. Opin. Chem. Biol. 2023, 74, 102310.
12. Yadav AK, Zhao Z, Weng Y, Gardner SH, Brady CJ, Pichardo Peguero OD, Chan J. Hydrolysis-resistant ester-based linkers for development of activity-based NIR bioluminescence probes. J. Am. Chem. Soc. 2023, 145, 2, 1460–1469.
11. Tapia Hernandez R, Lee MC, Yadav AK, Chan J. Repurposing cyanine photo-instability to develop NIR light-activatable nanogels for in vivo cargo delivery. J. Am. Chem. Soc. 2022, 144, 18101–18108.
10. Lucero MY, Gardner SH, Yadav AK, Borri A, Zhao Z, Chan J. Activity-based photoacoustic probes reveal elevated intestinal MGL and FAAH activity in a murine model of obesity. Angew. Chem. Int. Ed. 2022, 61, e202211774.
9. Yadav AK, Lee MC, Lucero MY, Reinhardt, CJ, Su S, Chan J. NIR bioluminescence probe enables discovery of diet-induced modulation of tumor microenvironment via nitric oxide. ACS Cent. Sci. 2022, 8, 461-472.
8. Gardner SH, Brady CJ, Keeton C, Yadav AK, Mallojjala SC, Lucero MY, Su S, Yu Z, Hirschi JS, Mirica LM, Chan J. A general approach to convert hemicyanine dyes into highly optimized photoacoustic scaffolds for analyte sensing. Angew. Chem. Int. Ed. 2021, 60, 18860–18866.
7. Yadav AK, Tapia Hernandez R, Chan J. A general strategy to optimize the performance of aza-BODIPY-based probes for enhanced photoacoustic properties. Methods in Enzymology, 2021, 657, 415-441.
6. Yadav AK, Hernandez S, Su S, Chan J. Acoustic-based chemical tools for profiling the tumor microenvironment. Curr. Opin. Chem. Biol. 2020, 57, 114-121.
5. Yadav AK, Reinhardt CJ, Arango AS, Huff HC, Dong L, Malkowski MG, Das A, Tajkhorshid E, Chan J. An Activity-based sensing approach for the detection of cyclooxygenase-2 in live cells. Angew. Chem. Int. Ed. 2020, 59, 3307-3314.
4. Yadav AK, Chan J. Bright dyes bring biology into focus. ACS Cent. Sci. 2017, 3, 920-921.
3. Abadi SSK, Tran M, Yadav AK, Adabala PJP, Chakladar S, Bennet AJ. New Class of Glycoside Hydrolase Mechanism-Based Covalent Inhibitors: Glycosylation Transition State Conformations. J. Am. Chem. Soc. 2017, 139, 10625-10628.
2. Perley-Robertson GE, Yadav AK, Winogrodzki JL, Stubbs KA, Mark BL, Vocadlo DJ. A fluorescent transport assay enables studying AmpG Permeases involved in peptidoglycan recycling and antibiotic resistance. ACS Chem. Biol. 2016, 11, 2626-2635.
1. Yadav AK, Shen DL, Shan X, He X, Kermode AR, Vocadlo DJ. Fluorescence-quenched substrates for live cell imaging of human glucocerebrosidase activity. J. Am. Chem. Soc. 2015, 137, 1181-1189.
Select Awards
2. C.S. Marvel Travel Award (2021)
1. TiMe Day Outstanding Research Poster Award (2019)